Paul L Kaufman Selected Research

1- (5- Isoquinolinesulfonyl)- 2- Methylpiperazine (H 7)

12/2010	Effect of H-7 on secondary cataract after phacoemulsification in the live rabbit eye.
8/2004	Effects of topical H-7 on outflow facility, intraocular pressure, and corneal thickness in monkeys.
8/2004	H-7 effect on outflow facility after trabecular obstruction following long-term echothiophate treatment in monkeys.

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Paul L Kaufman Research Topics

Disease

34	Glaucoma 09/2018 - 07/2002
9	Open-Angle Glaucoma (Glaucoma, Open Angle) 01/2018 - 01/2002
6	Ocular Hypertension (Glaucoma, Suspect) 01/2018 - 04/2007
5	Presbyopia 01/2016 - 03/2006
4	Miosis 07/2016 - 01/2004
2	Macular Edema 01/2019 - 01/2017
2	Ganglion Cysts (Ganglion) 08/2014 - 12/2009
2	Optic Nerve Diseases (Optic Neuropathy) 06/2006 - 07/2005
2	Hypotension (Low Blood Pressure) 10/2004 - 01/2004
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2017
1	Mydriasis 07/2016
1	Inflammation (Inflammations) 05/2015
1	Exfoliation Syndrome 10/2014
1	Capsule Opacification 12/2010
1	Chronic Disease (Chronic Diseases) 07/2009
1	Dehydration (Water Stress) 11/2008
1	Melanoma (Melanoma, Malignant) 04/2004
1	Gliosis 03/2003
1	Optic Nerve Injuries 03/2003
1	Blister (Bulla) 07/2002
1	Abscess 07/2002

Drug/Important Bio-Agent (IBA)

3	BOL 303259-XIBA 01/2018 - 06/2015
3	Latanoprost (Xalatan)FDA Link 07/2016 - 04/2004
3	latrunculin BIBA 09/2014 - 01/2004
3	1- (5- Isoquinolinesulfonyl)- 2- Methylpiperazine (H 7)IBA 12/2010 - 08/2004
2	AntioxidantsIBA 01/2017 - 10/2014
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 12/2010 - 06/2007
2	Calmodulin-Binding Proteins (Caldesmon)IBA 06/2006 - 06/2006
2	SteroidsIBA 06/2006 - 01/2002
2	Mitomycin (Mitomycin-C)FDA LinkGeneric 08/2002 - 07/2002
1	Fluocinolone Acetonide (Capex)FDA LinkGeneric 01/2019
1	Timolol (Blocadren)FDA LinkGeneric 01/2018
1	Ophthalmic Solutions (Eye Drops)IBA 03/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017
1	Ranibizumab (Lucentis)FDA Link 01/2017
1	Bevacizumab (Avastin)FDA Link 01/2017
1	Oxidants (Oxidizing Agents)IBA 01/2017
1	afliberceptIBA 01/2017
1	Oxygen (Dioxygen)IBA 01/2017
1	Adenosine Triphosphate (ATP)IBA 05/2015
1	CD39 antigenIBA 05/2015
1	MacrolidesIBA 09/2014
1	cresyl violetIBA 08/2014
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 08/2014
1	Benzalkonium Compounds (Benzalkonium Chloride)FDA LinkGeneric 03/2014
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2013
1	Memantine (Namenda)FDA Link 04/2012
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2011
1	ActomyosinIBA 12/2010
1	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2010
1	AnecortaveIBA 03/2010
1	alagebriumIBA 12/2009
1	NADPH Dehydrogenase (Dehydrogenase, NADP)IBA 12/2009
1	Calbindin 2IBA 12/2009
1	Synthetic Prostaglandins (Prostaglandin Analogues)IBA 11/2008
1	Ketamine FDA LinkGeneric 11/2008
1	OligonucleotidesIBA 09/2008
1	ProstaglandinsIBA 01/2008
1	Cholinergic Agents (Cholinergics)IBA 01/2008
1	EphrinsIBA 09/2007
1	Cholinergic AgonistsIBA 06/2007
1	Pilocarpine (Ocusert)FDA LinkGeneric 06/2007
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 06/2007
1	AndrogensIBA 06/2006
1	Androgen Receptors (Androgen Receptor)IBA 06/2006
1	Indicators and Reagents (Reagents)IBA 03/2006
1	Proteins (Proteins, Gene)FDA Link 07/2005
1	Peroxynitrous Acid (Peroxynitrite)IBA 01/2005
1	3-nitrotyrosineIBA 01/2005
1	Glutamic Acid (Glutamate)FDA Link 01/2005
1	Amino Acids FDA Link 01/2005
1	Retinaldehyde (Retinal)IBA 07/2004
1	Melanins (Melanin)IBA 04/2004
1	3R,5S)-2-((1E)-3,3-difluoro-4-phenoxy - 1- butenyl)- 3,5- dihydroxycyclopentyl)- 5- heptenoic acid (5Z)-7-((1R,2RIBA 04/2004
1	tafluprostIBA 04/2004
1	PhXa 85IBA 04/2004
1	prostaglandin F2alpha receptorIBA 04/2004
1	Matrix Metalloproteinase 14 (MT1-MMP)IBA 03/2003
1	Matrix Metalloproteinases (MMPs)IBA 03/2003
1	1,7- dioxa- 2,6- diaza- 4,7a- dithia- 3H,5H- benzo(cd)pentaleneIBA 01/2002
1	Fibronectins (Fibronectin)IBA 01/2002

Therapy/Procedure

12	Therapeutics 09/2018 - 12/2004
7	Lasers (Laser) 04/2012 - 03/2003
2	Trabeculectomy (Trabeculoplasty) 01/2013 - 04/2007
1	Catheters 01/2013
1	Slit Lamp 12/2010
1	Phacoemulsification 12/2010
1	Intraocular Injections 12/2009
1	Anesthesia 11/2008
1	Multifocal Intraocular Lenses 03/2006
1	Complementary Therapies (Alternative Medicine) 09/2005
1	Filtering Surgery 07/2002
1	Aftercare (After-Treatment) 07/2002